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Toxic Granulation

Toxic granulations are darker-coloured granules that can be seen under a microscope in neutrophils, the most abundant class of white blood cells. These granules are often larger and more abundant than normal granules. Their presence is non-specific and usually signals a bacterial infection or inflammation. They can also be observed in late-pregnancy, when the bone marrow is recovering after chemotherapy or after treatment with drugs (Neupogen©, Neulasta©, Grastofil©) that stimulate the formation of granulocytes (neutrophils) by the bone marrow.

Term of the Week

Predictive medicine

Medicine that links medical knowledge with data to predict a patient’s potential health problems. Examples include artificial intelligence and genetics.