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Hypergranulation

Toxic Granulation

Toxic granulations are darker-coloured granules that can be seen under a microscope in neutrophils, the most abundant class of white blood cells. These granules are often larger and more abundant than normal granules. Their presence is non-specific and usually signals a bacterial infection or inflammation. They can also be observed in late-pregnancy, when the bone marrow is recovering after chemotherapy or after treatment with drugs (Neupogen©, Neulasta©, Grastofil©) that stimulate the formation of granulocytes (neutrophils) by the bone marrow.

Term of the Week

Breast cancer

Breast cancer: This is a malignant tumour made up of many cancerous cells. It should be noted that breast cancer is not the most common cause of breast pain, as patients of this disease are often asymptomatic.