Crohn’s disease is a chronic and progressive inflammatory disease that can affect the entire digestive tract, but usually affects the lower part of the small bowel and the upper colon. This disease is caused by an abnormal response of the immune system that attacks healthy cells in the bowel (autoimmune reaction). The inflammation caused by the autoimmune reaction is responsible for various abdominal symptoms including pain and cramps, severe diarrhea, fatigue, weight loss and rectal bleeding. The diagnosis of Crohn’s disease is principally based on digestive symptoms, a positive stool calprotectin test, imaging (echography, MRI) and a colonoscopy. Crohn’s disease is treated mainly with anti-inflammatory drugs and surgery.