Skip to contentSkip to navigation
COVID-19: We are open. Some services are modified. Mask is mandatory. Details at

Standing Renin

Lying Renin

Renin is a protein produced by the kidneys in response to a drop in blood pressure in the renal artery. Renin promotes the production of angiotensin II, which in turn stimulates the secretion of aldosterone by the adrenal glands. Aldosterone plays a crucial role in maintaining blood volume and blood pressure. Any drop in blood pressure in the kidneys is, therefore, quickly corrected by the activation of the renin-angiotensin-aldosterone system. This test reports the amount (mass) of renin in the blood and must be interpreted with aldosterone levels based on the posture (lying or standing) at the time of sample collection. Results can be affected by many medications and dietary salt intake. The aldosterone/renin ratio can be measured to eliminate the effect of posture and other interferences.

High renin levels in the blood are often due to a drop in blood pressure in the renal artery (renal artery stenosis, heart failure, etc.). Low renin levels are most often due to hypertension of undetermined cause (essential hypertension) or caused by a benign tumour in the adrenal glands secreting aldosterone or another mineralocorticoid.

Term of the Week

Hot zone

A hot zone is a section of a facility (sometimes an entire facility or even a city district) where there is a high risk of contamination by patients with an infectious disease. All individuals entering a hot zone must respect appropriate protective measures. By analogy, “cold zone” and “warm zone” are used to refer to areas where there is no infected individual or only individuals suspected of having an infection.