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VCA IgM, Anti-Epstein-Barr Virus Viral-Capsid Antigen IgM


EBNA IgG and VCA IgM (anti-Epstein-Barr virus capsid antigen IgM) are two types of antibodies produced by the body against the Epstein-Barr virus (EBV), which is responsible for mononucleosis. EBNA IgG is directed against an antigen of the virus nucleus (Epstein Barr nuclear antigen), while the VCA IgM is directed against an element of the envelope (capsid) of the virus (viral-capsid antigen). When a person is infected with EBV, VCA IgM appears first and disappears within 4 to 6 weeks. EBNA IgG test results are positive within a few months, usually after symptoms have disappeared, and remain positive for life.

Term of the Week

Creatine Kinase MM (CK-MM)

CK (creatine kinase) is an enzyme (protein) found in several tissues, including muscles and the heart. Depending on the tissue, different forms of CK are present: CK-MM is primarily present in skeletal muscles, CK-MB represents 30% of CK from the heart, while CK-BB comes from the brain and smooth muscle, such as the intestinal walls. Atypical forms of CK (macro CK1 and macro CK2) can also be present. CK electrophoresis is most useful when muscular or cardiac disease does not seem to be responsible for the increased level of total CK.