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21 Hydroxylase Antibodies, 21-Hydroxylase Ab, 21-OH Ab, Adrenal Antibody, Hydroxylase Antibody, Anti-Adrenal Antibody

21-Hydroxylase Antibody

The 21-Hydroxylase Antibody test is used to investigate adrenal gland insufficiency and to assess a person’s risk of developing possible auto-immune adrenal gland insufficiency.

The adrenal glands (one gland on each kidney) are responsible for secreting cortisol, aldosterone, and other steroid hormones. Cortisol and aldosterone are vital hormones, and a malfunction of the adrenal glands (Addison’s disease) should be detected and treated quickly. 21-Hydroxylase is a protein involved in hormone synthesis by the adrenal glands.

Our immune system is responsible for defending our body against threats from cells and foreign organisms.

Often, it is deregulated and mistakes some of its own tissues for foreign tissues. The production of antibodies against the body’s own tissues is the cause of a large number of auto-immune diseases such as rheumatoid arthritis, juvenile diabetes, and several thyroid disorders.

Auto-antibodies are also the most frequent cause of Addison’s disease, on its own or often combined with other auto-immune conditions (hypothyroidism, pernicious anemia, type 1 diabetes, etc.). The presence of 21-Hydroxylase antibodies is compatible with established or developing Addison’s disease.

Term of the Week

Hot zone

A hot zone is a section of a facility (sometimes an entire facility or even a city district) where there is a high risk of contamination by patients with an infectious disease. All individuals entering a hot zone must respect appropriate protective measures. By analogy, “cold zone” and “warm zone” are used to refer to areas where there is no infected individual or only individuals suspected of having an infection.