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Pappenheimer Bodies

Pappenheimer bodies are small debris containing iron that can be found in red blood cells. This debris is normally eliminated by the spleen. Pappenheimer bodies are found in patients with no spleen (surgical splenectomy). They are also found in anemia through a defect in the synthesis of the “heme” part of hemoglobin (congenital sideroblastic anemia, or due to lead poisoning or advanced alcoholic cirrhosis) or when there is a congenital defect in the synthesis of one of the two protein chains that make up hemoglobin (thalassemia).

Term of the Week

Hot zone

A hot zone is a section of a facility (sometimes an entire facility or even a city district) where there is a high risk of contamination by patients with an infectious disease. All individuals entering a hot zone must respect appropriate protective measures. By analogy, “cold zone” and “warm zone” are used to refer to areas where there is no infected individual or only individuals suspected of having an infection.