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Red blood cells present in the blood are normally detached from each other. Rouleaux are clumps of red blood cells that look like stacked plates. They usually form as a result of abnormal quantities of certain proteins (immunoglobulin, fibrinogen) in the blood. Rouleaux are a non-specific indication of the presence of a pathology.

Red blood cell rouleaux are found in chronic inflammatory states and infections, multiple myeloma (excess synthesis of a single class of immunoglobulin by the bone marrow) and sometimes during pregnancy due to increased fibrinogen, the main coagulation protein.

Term of the Week

Hot zone

A hot zone is a section of a facility (sometimes an entire facility or even a city district) where there is a high risk of contamination by patients with an infectious disease. All individuals entering a hot zone must respect appropriate protective measures. By analogy, “cold zone” and “warm zone” are used to refer to areas where there is no infected individual or only individuals suspected of having an infection.