Howell-Jolly bodies are the nuclear remnants that can be found in red blood cells before their final maturation. These nuclear remnants are normally eliminated by the spleen. Howell-Jolly bodies are found in patients with no spleen (surgical splenectomy) or a spleen that does not function well (hyposplenism). They are also found in some red blood cell maturation disorders.
Breast cancer: This is a malignant tumour made up of many cancerous cells. It should be noted that breast cancer is not the most common cause of breast pain, as patients of this disease are often asymptomatic.