All Genotypes HPV. HPV 16, HPV 18, Human papillomavirus
HPV molecular test
Human papillomaviruses (HPV) are responsible for over 95% of cervical cancers. There are approximately 100 HPV subtypes, 13 of which are designated as "high risk". Of these, subtypes 16 and 18 alone account for more than 70% of cervical cancers. The HPV molecular test measures all of the "high-risk" subtypes and specifically indicates whether subtypes 16 and/or 18 are present.
HPV testing can be used alone, after an abnormal PAP test or in combination with liquid-based cytology (PAP test). The advantage of a liquid-based test is that molecular HPV detection and liquid-based cytology can be performed on the same specimen, saving patients multiple clinic visits. In women over the age of 25, HPV can be used alone every 5 years as a screening test, followed by the HPV molecular cascade test if necessary. Before this age, the presence of the virus is very common and the vast majority of infections heal spontaneously. In younger women, HPV testing should be done only after a PAP test showing suggestive cell abnormalities.
It should be noted that only a small percentage of chronic high-risk HPV infections will develop into cancer. A positive HPV, especially for subtypes 16 and/or 18, is however an indication for colposcopy, even if the PAP test does not yet show a significant abnormality.
Molecular HPV test
- Results available within 24 hours.
- Detection of HPV 16 and 18 subtypes or other high-risk subtypes.
- Liquid-based cytology reflex testing from the same specimen if needed
- Costs reimbursed by most insurers.
*A doctor's prescription is required.