
Pain Management PGx Test
It is time to finally get effective pain relief and get back to living your life.
The effect of medication is unique to each individual, which is why pharmacogenomics analyzes specific portions of DNA associated with certain drug classes.
The analysis identifies how each person is likely to respond to medication. The PGx Pain Management test helps you discover how your DNA influences whether a drug may cause side effects, be ineffective or provide symptomatic relief [1,2]. With your test results, your doctor is able to find the medication and dosage best suited to your needs.
Main categories of medication covered by the Pain Management PGx Test
Analgesic
- Acetaminophen (Tylenol®)
Opioid Antagonists
- Naloxone (Narcan®)
- Naltrexone (Revia®)
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
- Acetylsalicylic acid ( (Aspirin®)
- Celecoxib (Celebrex®)
- Diclofenac (Voltaren®)
- Etodolac (Ultradol®)
- Flurbiprofen (Ansaid®)
- Ibuprofen (Advil®)
- Indomethacine (Indocid®)
- Ketorolac (Toradol®)
- Meloxicam (Mobicox®)
- Nabumetone (Relafen®)
- Naproxen (Naprosyn®)
- Piroxicam (Feldene®)
- Tenoxicam (Mobiflex®)
Antimetabolite
- Methotrexate
Cannabinoids
- Cannabidiol (CBD)
- Nabilone (Cesamet®)
- Tetrahydrocannabinol (THC)
Opioids
- Buprenorphine (Butrans®)
- Butorphanol (Stadol®)
- Codeine
- Fentanyl (Duragesic®)
- Hydrocodone (Hycodan®)
- Hydromorphone (Dilaudid®)
- Meperidine (Demerol®)
- Methadone
- Morphine (Statex®)
- Nalbuphine (Nubain®)
- Oxycodone (Supeudol®)
- Remifentanil (Ultiva®)
- Sufentanil (Sufenta®)
- Tapentadol (Nucynta®)
- Tramadol (Ultram®)
Muscle Relaxant
- Carisoprodol (Soma®)
- Cyclobenzaprine (Flexeril®)
- Methocarbamol (Robaxin®)
- Tizanidine (Zanaflex®)
The comprehensive list of medications covered in Biron’s PGx test reports is available here.

Talk to your doctor about the test
Want to talk to your doctor about pharmacogenomic testing?
Download the documentation to start the conversation.
The benefits of Biron's Pain Management PGx Test



How does the pharmacogenomic test work?
Collect your sample

Receive your report and a free consultation

Complete PGx Pain Management test report
The report covers 40+ medications relevant to pain management. It contains important information that your doctor can use when deciding on the best treatment for you. Our experts are available to help you and your doctor interpret the results.
How are test results used by healthcare professionals?
Your healthcare professional will carefully review your medication history, current medications, diagnosis, and any other relevant medical information to determine the most suitable treatment for you.
Your genetic information is a valuable complement to other medical data. Genetics alone cannot predict your response to medication with absolute certainty. In some cases, the best option for you may be a drug with a cautionary statement in your report.

At Biron, safeguarding your privacy is our core commitment.
Ensuring the security and confidentiality of your information is a top priority for us. Your genetic data is encrypted on multiple levels and stored on Canadian servers that meet or exceed the most stringent security standards. No information is ever disclosed to third parties without your consent.
Biron offers exclusive content on genetics.
Are you curious? Get unmatched expertise and knowledge from our experts in our Education Center.
Frequently asked questions about genetic testing, pharmacogenomics, and nutrition
Can I do the test without a prescription?
Yes, but we recommend that you ask your doctor for one. What's more, if you have a prescription, you may be exempt from paying taxes.
My doctor doesn't know about the test, but I'd like to have it done.
We will be happy to provide your doctor with relevant information regarding the test. While genetic analysis helps predict how you might respond to different medications, many other factors can also play a significant role. By having access to your results, your healthcare professional will be able to put them in context with your overall health, allowing for more informed decision-making.
Can I combine this genetic test with others?
Yes, you can combine this test with any other test offered by Biron Genetics. Make your selection in the online store to see the available options and get the best bundled price.
Is DNA testing covered by insurance plans?
Coverage for genetic testing depends on your private insurance and plan.
A prescription may be required.
If you have a Health Spending Account with your insurance plan, you may be able to use this account to cover the cost of your genetic test. We recommend that you contact your insurance company for more information on your coverage. Get a quote for your genetic test and submit it to your insurance company.
Do I have to stop taking my medication to do the test?
No. Taking any prescribed or non-prescribed medication will have no influence on the pharmacogenomic test. However, it is not advisable to stop or modify your current treatments without the approval of a healthcare professional. We therefore recommend that you continue your treatments as directed by your healthcare professional.
What are the indications for pharmacogenomic (PGx) testing in ADHD?
PGx testing may be helpful in patients with ADHD who experience one or more of the following:
Side effects at low medication doses or failure of at least two psychostimulants
Presence of comorbid conditions requiring the use of an antidepressant (e.g., depression, anxiety)
Reluctance to try a new medication; PGx strengthens confidence in therapeutic decision-making
Which ADHD medications are included in the PGx test?
The PGx report determines how genetics influence blood levels and the effects of medications used to treat ADHD, including:
Amphetamine-based psychostimulants:
Amphetamine/Dextroamphetamine (Adderall XR®), Lisdexamfetamine (Vyvanse®), Dextroamphetamine (Dexedrine®)
Methylphenidate-based psychostimulants:
Concerta®, Biphentin®, Foquest®, Quillivant® ER, Ritalin® SR
Non-psychostimulants
Guanfacine XR (Intuniv XR®), Atomoxetine (Strattera®)
Because the report notifications are based on the availability of evidence from peer-reviewed scientific literature, some medications have the “Normal efficacy” or “Normal risk” notifications. This indicates that there is currently no evidence available to determine a potential impact of genetics on the medication’s effect. Please refer to a sample report to see which medications carry these notifications.

Avoid the lengthy process of trial and error. Order your test today.
Sources2
- Smith et al. CYP2D6-guided opioid therapy improves pain control in CYP2D6 intermediate and poor metabolizers: a pragmatic clinical trial. Genet Med
- Swen et al. A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study (2023) Lancet












