
The Biron Pharmacogenomic (PGx) Test for mental health, ADHD, and pain management
Let your DNA help you find the right medications.
The Biron PGx test
The Biron Pharmacogenomic Test (PGx) is a DNA test that allows your doctor to predict certain risks associated with medications and make better drug choices based on your genetics.
What are the benefits of a pharmacogenomic test?
The Biron PGx test evaluates select portions of your DNA to determine how these affect your response to medications. The test looks at how your results from three perspectives:
Pharmacogenomics increases remission rates and reduces the risk of side effects [1] [2].
Get better, faster than with standard trial-and-error
- 145 medications used for mental health and pain management.
- 44 genes tested.
- This is not a blood test, you only need to provide a saliva sample.
How does it work?
1. Provide your saliva sample
2. Return your sample
3. Receive your report
For more details regarding how to take your saliva sample, click here.
To download your report, log in to the Biron Genetics portal.
How will this report be used by your healthcare provider?
When you take a test, the results will be sent to your physician within 5 to 10 business days of receiving the sample at our laboratory. You will receive an email to download your report.
To maximize the benefits of this test, we encourage you to share your results with any other healthcare provider (physician, pharmacist, etc.) that may prescribe or adjust your medications.
Based on your results, your physician may choose to :
- Adjust your doses
- Choose medications that may be more compatible based on your genetics
- Avoid prescribing or monitor more closely medications that have a high risk of causing side effects
Ultimately, your provider's final choice will take into account your medication history and current medications, your diagnosis, and all other relevant medical information. Since genetics does not always predict with 100% certainty your reaction to medications, the best option for you may be a medication with an alert in your PGx report.
Does your doctor have any questions regarding the Biron PGx Test? Share this link with your healthcare provider.
Frequently asked questions - FAQ
What type of sample is required for this test?
This analysis only requires a small amount of saliva (1mL).
Is the quantity of saliva collected important?
Yes, make sure that the amount of saliva collected in the tube is close to the top line. If there is too much saliva for the amount of stabilizing liquid, your sample will be rejected once it arrives at the lab. If there isn't enough saliva, there won't be enough DNA to proceed with the analysis.
Should I stop taking my medication before I do a pharmacogenomic test?
No, the current prescribed or non-prescribed treatments you are taking will not influence the results of a pharmacogenomic test. It is not advised to stop or alter your current treatment. You may continue your treatments as advised by your health-care professional.
If i'm drinking a coffee, can I do the test?
It is important that you don't drink, eat, or smoke 30 minutes before collecting your sample. Your saliva should be clear. Please wait 30 minutes after brushing your teeth as well.
Can the weather affect my sample on its way to the lab?
No, the stabilizing liquid found in the top part of the tube will protect your DNA from any temperature variations.
When will I receive my results?
You should expect a delay of 5 to 10 business days from the moment your sample is received at the lab.
How will I receive my pharmacogenomic test report?
Your genetic report will be sent to your attending physician who will conact you for a medical follow up and share his recomendations.
Do I need a prescription to take a pharmacogenomic test?
No, a prescription is not required, but we recommend that you ask your doctor for one. If you have one, the test will be exempt from taxes. The words 'Pharma Profile, 'Pharmacogenomic test' or 'genetic analysis for medication' as well as your diagnosis(es) (e.g. ADHD, Depression, Anxiety, etc.) must appear on the prescription for it to be valid. A prescription written for a specific medication (e.g. Ritalin) is not valid.
Some insurers may require a prescription for the reimbursement of your test.
Why is it important that I share my results with a health-care professional?
Although a genetic analysis helps predict your response to different drugs, many other factors come into play. A health-care professional will put your genetic results into the context of your overall health for better decision-making.
How can I share my results with another health-care professional?
Please send your request to genetics@biron.com or call 1 855-943-6379 and we will send them a copy of your report.
Can my results be used for my relatives?
Some of your genetic results will be similar to those of your relatives. However, since you do not share 100% of your DNA with them, there will be differences (with the exception of identical twins). Therefore, each member of the family should take the test to obtain their unique results.
Is my test covered by my private insurance?
A prescription could be required. If so, please make sure it says' Pharmacogenomic test'. If you have a wellness spending account in your insurance plan, you could use this account to cover the cost of this test. We recommend that you contact your insurance company for more information on your coverage.
Is my genetic data secure?
Your genetic data is encrypted on multiple levels and stored on Canadian servers that meet or exceed the most stringent security standards. Our SOC2 Type 2 certification is tested annually by an external auditor to ensure the robustness of our systems. Biron protects access to your genetic data by letting you control who can access your information.
Will my DNA be kept by Biron?
Your saliva sample will be destroyed no later than 4 weeks after the analysis. In accordance with Canadian medical laboratory regulations, all data must be encrypted and saved for a minimum period determined by the 'Ordre des Technologistes Médicaux', which varies according to the lifespan of the lab equipment used. If you have any concerns, please contact renseignementspersonnels@biron.com
Will you share my genetic results?
Your results will never be shared with a third party without your consent. Whether it's your doctor, your insurer or your family, we will always ask for your consent.
Will you share my genetic results with my insurance company? Will they refuse me or increase my premiums?
If an insurance company asks if you've had a genetic test, you don't have to answer. You can refer them to Bill S-201.
Will I learn about genetic diseases with the Pharmacogenomic test?
This test is not a diagnostic analysis for diseases. Rather, it is a decision-making tool to optimize the treatment of a condition. Based on accepted scientific data, your results cannot be used to make any diagnosis or to predict your risk of developing any health problem.
Will the test examine my entire genome?
No. We don't sequence your entire genome. We use a technique called "genotyping" to analyze only the parts of your DNA we need to produce our reports; a total of 105 genetic variants.
How long are my results valid for?
Since your genetic code does not change, the results will be the same whether you take the test at age 7 or age 70. However, science evolves and it is possible that the interpretation of your results may change over time. If this is the case, your report will be updated at no extra charge, to ensure that you and your doctor have the most up-to-date and scientifically accurate information possible. Additional charges may apply if further genetic analysis is required.
Where do Biron's Pharmacogenomic test recommendations come from?
The recommendations included in our reports are drawn from peer-reviewed scientific publications. Some recommendations may also come from drug labels issued by Health Canada and other agencies such as the Food and Drug Administration (FDA). Biron ensures that the information included in your report comes from credible, expert scientific sources.
Are your test results guaranteed?
Since many factors influence drug response, following the recommendations in your report will not entirely eliminate the possibility that your body may not respond optimally to certain medications.
By following the recommendations in your report, you will reduce your risk of undesirable side effects from medication and increase your chances of obtaining effective treatment.
The report contains an interpretation of the results based on independent scientific studies and guidelines. The genetic analyses on which the recommendations are based are validated and 99.99% reliable.
How long has Biron been offering pharmacogenomic testing?
Biron has been one of Quebec's leading healthcare providers since 1952. In 2015, Biron joined forces with BiogeniQ, a genetics company founded in 2013.
If you still have questions or concerns, contact us at genetics@biron.com or at 1 855-943-6379.
Sources2
- Swen et al. A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study (2023) Lancet
- Brown et al. The clinical utility of combinatorial pharmacogenomic testing for patients with depression: a meta-analysis (2020) Pharmacogenomics.